<html><head><meta name="color-scheme" content="light dark"></head><body><pre style="word-wrap: break-word; white-space: pre-wrap;">%% ============================================================================
 % !Mode:: "TeX:UK:UTF-8"
 % !TEX program = XeLaTeX
 % -----------------------------------------------------------------------------

% Private XeLaTeX style for scientific texts
% copyright 2019 by Dr Engelbert Buxbaum &lt;engelbert_buxbaum@web.de&gt;
% This file may be shared under Gnu copyleft or the LaTeX the Project Public License.

\ProvidesPackage{manual}[2019/09/18 v1.01 standard packages for scientific texts]
\NeedsTeXFormat{LaTeX2e}

\RequirePackage{kpfonts-otf}
\usepackage{polyglossia}%foreign language support

\RequirePackage{acronym}%keep track of acronyms
%\RequirePackage{amssymb}%math symbols, not required with kpfonts-otf
\RequirePackage[backend=biber,bibencoding=UTF8,sorting=none,dateera=christian,style=numeric-comp]{biblatex}%bibliography
\RequirePackage{biochemistry-colors}%defines standard-conform colours for biochem entities
\RequirePackage{booktabs}%proper rules in tables
\RequirePackage{chemarrow}%arrows in chemical reactions
\RequirePackage{colortbl}%coloured background for tables
\RequirePackage{csquotes}%context-sensitive quotes, required for biblatex
\RequirePackage{css-colors}% defines web-safe colours
\RequirePackage{doi}%give DOIs as hyperlinks in bibliography
\RequirePackage{floatrow}%control float placement
\RequirePackage{fontspec}% font selecting commands
\RequirePackage{graphicx}%inclusion of images
\RequirePackage{hypcap} % anchors of captions
\RequirePackage[british]{isodate}%use international format for date and time
\RequirePackage{isotope}%correct typesetting of isotopes
\RequirePackage{letltxmacro}% change LaTeX commands with optional arguments
\RequirePackage{listings}%typeset computer code
\RequirePackage{lscape}%typeset wide material in lanscape mode
\RequirePackage{makeidx}%index generation
\RequirePackage{marvosym}%various symbols
\RequirePackage{mathbbol}%blackboard bold symbols (double line left)
\RequirePackage{mathtools}%extension of amsmath
\RequirePackage{media9}%include video or sound, currently doesn't work because flash-based
\RequirePackage{microtype}%micro-typesetting
\RequirePackage{multicol}%switching between one- and multicolumn
\RequirePackage{placeins}%allows FloatBarriers to be set
\RequirePackage{rotating}%rotate objects} sidewaystables/figures
\RequirePackage{siunitx}%correct typesetting of units
\RequirePackage[labelformat=empty,labelsep=none]{subfig}% several entries in one float
\RequirePackage{supertabular}%tables over several pages
\RequirePackage[breakable,skins,listings]{tcolorbox}%put text into coloured boxes
\RequirePackage[euler]{textgreek}%upright greek characters
\RequirePackage{ulem}%underlining and striking out
\RequirePackage{url}%typeset internet links (preloaded in beamer)
\RequirePackage{wasysym}
\RequirePackage{xcolor}%handle colours

%\RequirePackage{pdfcomment}% use pdf annotations

\RequirePackage{hyperref}%hyperrefs in PDF, must be last package called, preloaded in beamer
\hypersetup{final=true,
            pdfauthor={Dr. Engelbert Buxbaum},
            colorlinks=true,
            citecolor=Blue,%bibliography, dark blue
            linkcolor=Blue,%internal links, dark blue
            urlcolor=DodgerBlue,%internet, middle blue
            allbordercolors=White}

\newcommand{\EURO}{{\footnotesize{\EUR}}} % because \EUR is way too big

\DeclareSIUnit\angstrom{\text{��}}
\sisetup{% set-up for siunitx and XeTeX
         print-unity-mantissa = false,
         separate-uncertainty,
         negative-color = red
        }

% special chars in listings environment under XeTeX
\lstset{literate=%
    {��}{{\"O}}1
    {��}{{\"A}}1
    {��}{{\"U}}1
    {��}{{\ss}}1
    {��}{{\"u}}1
    {��}{{\"a}}1
    {��}{{\"o}}1
    {~}{{\textasciitilde}}1
    }

\let\wasymale\male                        % start to undo overwriting of wasy by kpfonts_otf
\let\wasyfemale\female                    % complete after \begin{document}
% after \begin{document} add:
%\let\male\wasymale
%\let\female\wasyfemale

\setmainlanguage{en-GB}
\setotherlanguage{arabic}
\setotherlanguage{russian}
\setotherlanguage{greek}

\newfontfamily\arabicfont[Script=Arabic]{FreeSerif}
\newfontfamily\russianfont{FreeSerif}
\newfontfamily\greekfont{FreeSerif}


\newcommand{\Name}[1]{\textsc{#1}}        % proper names
\newcommand{\Foreign}[1]{\textit{#1}}     % words from foreign languages
\newcommand{\Species}[1]{\textit{#1}}     % biological species

% Fonts for math-entities
\newcommand{\skalar}[1]{\ensuremath{#1}}
\newcommand{\Vector}[1]{\ensuremath{\vec{\mathfrak{#1}}}}
\newcommand{\AbsVec}[1]{\ensuremath{\mathfrak{#1}}}
\newcommand{\arr}[1]{\ensuremath{\mathcal{#1}}}
\newcommand{\tensor}[1]{\textsf{\bfseries{#1}}}
\newcommand{\set}[1]{\ensuremath{\mathbb{#1}}}

% move super- and subscripts to make them more readable
\makeatletter
  \frozen@everymath={\check@mathfonts
    \fontdimen16 \textfont2=\fontdimen17 \textfont2
    \the\everymath}
  \frozen@everydisplay={\check@mathfonts
    \fontdimen16 \textfont2=\fontdimen17 \textfont2
    \the\everymath}
\makeatother

%% "closed" sqrt sign, https://tex.stackexchange.com/questions/29834/closed-square-root-symbol

\LetLtxMacro{\OldSqrt}{\sqrt}
\newcommand{\ClosedSqrt}[1][\hphantom{3}]{\def\DHLindex{#1}\mathpalette\DHLhksqrt}
\makeatletter
    \newcommand*\bold@name{bold}
    \def\DHLhksqrt#1#2{%
        \setbox0=\hbox{$#1\OldSqrt{#2\,}$}\dimen0=\ht0\relax%
        \advance\dimen0-0.2\ht0\relax% size of the added box is still 0.2 times ht0
        \setbox2=\hbox{\vrule height\ht0 depth -\dimen0}%
        {\hbox{$#1\expandafter\OldSqrt\expandafter[\DHLindex]{#2\,}$}
        \lower\ifx\math@version\bold@name0.6pt\else0.4pt\fi\box2}
    }
    % root index positioning and added space at the end, mostly noticeable in inline math mode
    \renewcommand*{\sqrt}[2][\ ]{\ClosedSqrt[\leftroot{-2}\uproot{1}#1]{#2}\kern0.1em}
\makeatother

\DeclareMathOperator{\logit}{logit}
\DeclareMathOperator{\sgn}{sgn}
\DeclareMathOperator{\diag}{diag}
\DeclareMathOperator{\var}{var}
\DeclareMathOperator{\cov}{Cov}
\DeclareMathOperator{\trace}{tr}
\DeclareMathOperator{\abs}{abs}
\DeclareMathOperator{\rk}{rk}
\DeclareMathOperator{\svd}{svd}
\DeclareMathOperator{\median}{median}
\DeclareMathOperator{\dist}{dist}
\DeclareMathOperator{\ld}{ld}
\DeclareMathOperator{\modulo}{modulo}

% physicochemical entities
\newcommand{\ph}{\Foreign{p}H}
\newcommand{\poh}{\Foreign{p}OH}
\newcommand{\pka}{\Foreign{p}K\textsubscript{a}}
\newcommand{\pkb}{\Foreign{p}K\textsubscript{b}}
\newcommand{\pkw}{\Foreign{p}K\textsubscript{w}}
\newcommand{\pkr}{\Foreign{p}K\textsubscript{r}}
\newcommand{\pI}{\Foreign{p}I}

% Chemical formulas in text
\makeatletter
 \DeclareRobustCommand{\single}{\raisebox{0.25ex}{$\m@th-$}}
 \DeclareRobustCommand{\dotted}{\raisebox{0.6ex}{$\m@th.. $}}
 \DeclareRobustCommand{\Lewis}{\raisebox{0.6ex}{$\m@th.$}}
 \DeclareRobustCommand{\double}{\raisebox{0.25ex}{$\m@th=$}}
 \DeclareRobustCommand{\triple}{\raisebox{0.25ex}{$\m@th\equiv$}}
 \DeclareRobustCommand*{\Doth}{\LARGE{.}}
 \DeclareRobustCommand{\radic}{\hspace{-0.1em}{\raisebox{1.4ex}{\Doth}}}
 \DeclareRobustCommand{\chemical}[1]{%
    {\(\m@th
     \edef\resetfontdimens{\noexpand\)%
         \fontdimen16 \textfont2=\the\fontdimen16 \textfont2
         \fontdimen17 \textfont2=\the\fontdimen17 \textfont2 \relax}%
     \fontdimen16 \textfont2=2.7pt \fontdimen17 \textfont2=2.7pt
     \mathsf{#1}%
     \resetfontdimens}}
\makeatother
\renewcommand{\isotopestyle}{\mathsf}% if package isotope is used

% use academic colours: philosophers blue, physicians green, lawyers red, theologists black
\newtcolorbox{advanced}[1]{colback=blue!5!white,colframe=blue!75!black,fonttitle=\bfseries,title=#1,breakable}
\newtcolorbox{medical}{colback=green!5!white,colframe=green!75!black,breakable}
\newtcolorbox{medtitle}[1]{colback=green!5!white,colframe=green!75!black,fonttitle=\bfseries,title=#1,breakable}
\newtcolorbox{rules}{colback=red!5!white,colframe=red!75!black,breakable}

\lstloadlanguages{[Borland6]Pascal,R,[x86masm]assembler}
\lstset{backgroundcolor=\color{Cornsilk},
        language=[Borland6]Pascal,
        alsolanguage=[x86masm]assembler,
        alsolanguage=R,
        extendedchars=false,                 % chars 128-255 not printed
        breaklines=true,                     % long lines broken
        breakatwhitespace=true,              % ... but only at whitespace
        numbers=left, numberstyle=\tiny, stepnumber=1, numbersep=0pt,
        basicstyle=\ttfamily\small\color{black}, % print listing small monospaced
        keywordstyle=\bfseries,
        identifierstyle=\color{DarkRed},     %
        morecomment=[l]{//},                 % allow inline comments from Object Pascal
        commentstyle=\color{Blue},
        stringstyle=\color{DodgerBlue},
        showstringspaces=false               % no special string spaces
       }
\defaultfontfeatures{Scale=MatchLowercase}
\setmonofont{Fantasque Sans Mono}            % 0O, 1Il -~ clearly distinguished, Jany Belluz &lt;jany.belluz@hotmail.fr&gt;

% definitions for biblatex     http://www.khirevich.com/latex/biblatex/, https://3d.bk.tudelft.nl/hledoux/blog/fiddling-biblatex/,
% moewe94@live.de on comp.text.tex, https://tex.stackexchange.com/questions/211199/changing-the-position-of-the-editor-with-biblatex-inbook

\DeclareNameAlias{sortname}{last-first}

\renewcommand{\multinamedelim}{\addcomma\space}
\renewcommand{\finalnamedelim}{\addspace\&amp;\space}

\DefineBibliographyStrings{british}{%
        andothers = {\textit{et\addabbrvspace al\adddot}},
        editor    = {(ed\adddot):},
        editors   = {(eds\adddot):},
        byeditor  = {(ed\adddot):},
}

\DefineBibliographyStrings{german}{%
        andothers = {\textit{et\addabbrvspace al\adddot}},				
        editor    = {(Hrsg.):},
        editors   = {(Hrsg.):},
        byeditor  = {(Hrsg.):},
}

%(ed.) after name list:

\renewbibmacro*{byeditor+others}{%
  \ifnameundef{editor}
    {}
    {\printnames[byeditor][1-1]{editor}%
     \setunit{\addspace}%
     \usebibmacro{byeditor+othersstrg}%
     \clearname{editor}%
     \newunit}%
  \usebibmacro{byeditorx}%
  \usebibmacro{bytranslator+others}}

\renewcommand{\emph}[1]{\textnormal{\textit{#1}}}
\renewcommand*{\mkbibnamefamily}[1]{\textnormal{\textsc{#1}}}       %
\renewcommand{\newunitpunct}{\addspace\midsentence}
\DeclareDelimFormat[bib]{nametitledelim}{\addcolon\space}           %Doppelpunkt nach Namen, kein Punkt
\DeclareFieldFormat[article,inbook,incollection,inproceedings,patent,thesis,unpublished]{title}{\textnormal{#1}\addcomma} % keine Anf��hrungszeichen um Titel und kursiv
\DeclareFieldFormat{journaltitle}{\mkbibemph{#1}}                   % italic journal title, no comma
\DeclareFieldFormat[inbook,thesis]{title}{\mkbibemph{#1\addcomma}}  % italic title with comma
\DeclareFieldFormat[article]{title}{#1\addcomma}                    % title of journal article is printed as normal text
\DeclareFieldFormat{titlecase}{#1}                                  % keine ��berm����ig vielen Gro��buchstaben im Titel
\DeclareFieldFormat[article]{volume}{\mkbibbold{#1}}                % Volume in bold
\DeclareFieldFormat[article]{number}{#1}                            % issue textnormal
\DeclareFieldFormat{pages}{#1}				                        % Kein Pr��fix der Seitenzahlen

\renewbibmacro*{volume+number+eid}{%
   \printfield{volume}%
   \setunit{\addcolon}%
   \printfield{number}%
  }

\DeclareSourcemap{
   \maps[datatype=bibtex]{
     \map{
       \step[fieldset=pagetotal, null]
      }
    }
  }
\renewbibmacro{in:}{%
  \ifentrytype{article}{}{\printtext{In\intitlepunct}}
  }

% ------ setup for document

\floatsetup[table]{style=plaintop}
\setlength{\rotFPtop}{10pt plus 1fil} % quick fix for sidewaysfigures appearing to high, so that caption is cropped

\frenchspacing

\hyphenation{ATP-ase GTP-ase dia-be-tes phy-sio-logi-cal bio-lo-gy
pro-teo-ly-sis trans-cy-to-sis hy-dro-ly-sis telo-mere hy-dro-lysed
im-mu-no-glo-bu-lin Cali-for-nia mini-mum mini-ma phos-pha-ti-dyl pyro-phos-phate
phos-pho-pro-tein}

\makeatletter % \provideenvironment in analogy to \providecommand, https://tex.stackexchange.com/questions/20687/does-newenvironment-have-a-provideenvironment-cousin-as-newcommand-has-prov
\def\provideenvironment{\@star@or@long\provide@environment}
\def\provide@environment#1{%
        \@ifundefined{#1}%
                {\def\reserved@a{\newenvironment{#1}}}%
                {\def\reserved@a{\renewenvironment{dummy@environ}}}%
        \reserved@a
}
\def\dummy@environ{}
\makeatother

% Abstracts in book + scrbook
\providecommand\abstractname{Abstract}% doesn't change pre-existing command
\provideenvironment{abstract}[1]{%
  \begin{center}\normalfont\bfseries\abstractname\end{center}
  \begin{quotation} #1 \end{quotation}
  }{%
  \vspace{1cm}
  }
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